Molecular Info® Copy Right © 2001
Institute of Molecular Development LLC
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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KONRAD T. HOWITZ, KEVIN J. BITTERMAN, HAIM Y. COHEN,
DUDLEY W. LAMMING, SIVA LAVU, JASON G. WOOD, ROBERT E. ZIPKIN, PHUONG CHUNG, ANNE KISIELEWSKI, LI-LI ZHANG, BRANDY SCHERER & DAVID A. SINCLAIR
The Nature, September 2003, 425, 191-196
Increased activity of sirtuin, a deacetylase, promotes life span in yeast, C. elegans, and human.
Polyphenols are found to activate sirtuin resulting increased life span in yeast.
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