Molecular
Info® Copy Right © 2001
Institute of Molecular Development LLC
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Trophic Conversion of an Obligate Photoautotrophic Organism Through Metabolic Engineering
L.A. Zaslavskaia, J.C. Lippmeier, C. Shih, D. Ehrhardt, A.R. Grossman and K.E. Apt
The Science, 292: 2073-2075, June 2001.
By introducing a single human glucose-transporter gene, the marine alga
Phaeodactylum tricornutum lives off sugar and grow in the dark. In human, this gene
encodes a protein that imports glucose through the membranes of red blood cells. This
demonstrates that a fundamental change in the metabolism of an organism can be accomplished
through the introduction of a single gene.
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