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    Short interfering RNA confers intracellular antiviral immunity in human cells

    LEONID GITLIN, SVETA KARELSKY & RAUL ANDINO

    The Nature, May 2003, 423, 197 (Nature 418, 430 - 434, 2002)
    The antiviral effect of double strand, small interfering RNA is sequence-specific. Gene silencing is not attributable to classical antisense mechanisms.