Molecular Info®

Molecular Info® Copy Right © 2001 Institute of Molecular Development LLC

Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIR1 in mediating auxin response Claus Schwechheimer, Giovanna Serino, Judy Callis, Willaim L. Crosby, Svetlana Lyapina, Raymond J. Deshales, William M. Gray, Mark Estelle, Xing-Wang Deng Science, Vol 292, 1379-1382, May 18, 2001 Plants with reduced COP9 signalosome levels had decreased auxin response similar to loss-of-function mutants of the E3 ubiquitin ligase SCFTIR1. The COP9 signalosome was required for efficient degradation of PSIAA6, a candidate substrate of SCFTIR1.